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Purple Longevity

  Purple Longevity is a powerful anti-aging complex of botanical extracts which research has shown to be effective in delaying and resversing the aging process.  

Purple Longevity(TM) and Male Sexual Anti-Aging

  • Purple Longevity is a powerful anti-aging blend of Trans-Resveratrol and Grape Extracts.
  • Trans-Resveratrol has been shown to extend the lifespan of animals. 
  • Studies indicate that Resveratrol activates the SIRT1 gene in humanswhich has been referred to as the "anti-aging" gene. Researchers propose that SIRT1 acts as a regulator of energy expenditure in the body, and has been shown to increase energy production, and improve physical activity levels in laboratory research  conducted on animals.
  • Resveratrol and Grape extracts (as powerful antioxidants and nitric oxide stimulators) provide support for the health of the cardiovascular system.
  • In terms of nitric oxide stimulation, both resveratrol and the polphenol fractions from the grape extracts induce the synthesis of nitric oxide by vascular endothelial cells. This further results in vasorelaxation of the vascular smooth muscle, an important element in establishing an erection. 
  • The colorful purple pigment in grape skins, called anthocyanidins, inhibit the action of the PDE5 enzyme in smooth muscle. PDE5 degrades the cGMP molecules (important for the enabling a penile erection) in the penis. By inhibiting PDE5, levels of the molecule cGMP are increased, thus enabling the prolonging vasorelaxation and erection. cGMP is the end result of nitric oxide production. Many of the current prescription medicines for erectile dysfunction work on this principal. 

References:

(1) Valenzano DR, et al. Resveratrol and the Pharmacology of aging: a new vertebrate model to validate an old molecule. Cell Cycle. 2006 May;5(10):1027-32.

(2) Lagouge M, et al. Resveratrol improves mitochondrial function and protects against metabolic diseases by activating SIRT1 and PGC-1alpha. Cell. 2006 Nov 15.

(3) Bauer J, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006. Nov 1.

(4) Wallerath T, et al. A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase. Nitric Oxide. 2005 Mar;12(2):97-104

(5) Rathel TR, et al. Activation of endothelial nitric oxide synthase by red wine polyphenols: impact of grape cultivars, growing area and the vinification process. J Hypertens. 2007 Mar;25(3):541-9

(6) Soares De Moura R., et al. Antihypertensive, vasodilator and antioxidant effects of vinifera grape skin extract. J Pharm Pharmacol 2002 Nov; 54(11): 1515-20

(7) Siva B, et al. Effect of polyphenolics of grape seeds (GSE) on blood pressure (BP) in patients with metabolic syndrome (MetS). FASEB 2006. San Francisco, CA

(8) Dell'Agli M, et al. In vitro inhibition of human cGMP-specific phosphodiesterase-5 by polyphenols from red grapes. J Agric Food Chem. 2005 Mar 23;53(6):1960-6

(9) Corbin JD. Mechanisms of action of PDE5 inhibition in erectile dysfunction. Int J Impot Res. 2004 Jun;16 Suppl 1:S4-7 

 
 
 
 
 
 
 
 
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